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Clinical Medicine Director

Valid until Jun. 30, 2025

Primary Responsibilities:

1. Responsible for the overall planning of clinical research, including the investigation of clinical trial progress and relevant information of similar varieties at home and abroad, clinical evaluation and feasibility analysis, and the formulation of clinical development strategy;

2. Be responsible for the formulation of the company's project clinical research scheme, communicate with clinical medical experts and review experts in the process of clinical scheme design and clinical research, and preside over internal scheme discussion, external scheme consultation meeting and project related professional meetings;

3. Be responsible for clinical academic support during the development of clinical trial projects, such as the writing, review and revision of CRF, informed consent, investigator manual, etc;

4. Write, review and revise clinical application materials such as clinical summary report and clinical research review;

5. Be responsible for the clinical program training of other members of the project team and medical academic support during the development of clinical trials, such as medical audit and medical quality assurance;

6. Set up a medical team, cooperate with the clinical operation team to ensure that the clinical trial is carried out as planned, and answer / communicate relevant questions / information in the clinical of the product;

7. Other related work arranged by the company.


Qualifications:

1. Medical doctor, more than 5 years of clinical research experience in pharmaceutical R & D enterprises or CRO, familiar with the field of metabolism is preferred;
2. Be familiar with ind, clinical phase I to III trials, and have strong clinical trial design and evaluation ability;
3. Have solid basic medical knowledge; Familiar with ICH-GCP requirements; Familiar with drug clinical development business process and regulatory requirements;
4. Good English reading ability and basic medical writing, fluent oral communication;
5. Have rich project management experience, good communication skills and cross departmental cooperation ability.


*Application email to:hr@cascadepharm.com
BD Head

Valid until Jun. 30, 2025

Primary Responsibilities:

1. Organized the investigation and analysis of clinical needs, drug targets and R&D pipelines in related disease fields, and participated in the formulation of the company's R&D direction and R&D strategy

2. Formulated the commercialization strategy and plan of the company's R&D pipeline according to the company's objectives and strategies

3. Responsible for the exploration, relationship establishment and maintenance of potential partners at home and abroad

4. Organized domestic and foreign business promotion of related projects, communicated and negotiated with foreign prospective customers, coordinated internal and external relations to complete license out transactions and enhance company value

5. Overall management of R&D cooperation with external institutions, establishment of cooperation framework system, control cooperation risks, and improve cooperation development efficiency

6. Other work arranged by the company


Qualifications:

1. Doctor degree in biology or medicine (MBA degree is preferred), with insight into business competition

2. More than five years of work experience as BD Director, led the license out of the project, had extensive resources and contacts in the industry, and had successful cases of BD deal

3. Familiar with clinical needs, drug targets and pipeline research and development in related disease fields, and familiar with the competitive landscape

4. Fluent English, excellent cross-cultural communication skills, business negotiation skills, familiar with transaction rules

5. Have strong ambition and good professional ethics

6. Good coordination ability and sense of inter-departmental collaboration


*Application email to:hr@cascadepharm.com
(Senior) Director of Chemistry

Valid until Jun. 30, 2025

Primary Responsibilities:

  1. Lead the Discovery and Development of Small Molecule Drugs

    • Conduct research and evaluation of drug targets.

    • Apply expertise in chemistry and pharmacy for professional analysis.

    • Design and optimize small molecules, including       structure-activity relationship (SAR) studies, optimization of ADMET       properties, and physicochemical characteristics to enhance druggability.

    • Design synthetic routes and screen, evaluate, and identify       clinical candidate compounds.

  2. Manage Multiple Projects

    • Oversee the implementation and progress of multiple projects.

    • Efficiently utilize internal and external resources to address       medicinal chemistry challenges in project advancement.

  3. Collaborate Effectively Across Teams

    • Work collaboratively with internal and external stakeholders       to lead R&D efforts.

    • Ensure smooth execution of company research strategies and       R&D projects.

  4. Literature Research and Intellectual Property Management

    • Conduct literature research and gather relevant information in       drug development.

    • Lead the development of intellectual property protection       strategies and patent planning for projects.

  5. Project Summaries and Reporting

    • Regularly summarize project progress and provide comprehensive       reports.

  6. Other Responsibilities

    • Perform additional tasks as assigned by the company.



Qualifications:

  1. Educational Background

    • Ph.D. in Organic Chemistry, Medicinal Chemistry, or a related       field.

    • Over 10 years of experience in small-molecule innovative drug       development, with expertise in drug molecule design.

  2. Comprehensive Knowledge of Drug Development

    • Familiarity with the full process of new drug development.

    • Strong analytical and problem-solving skills, with a knack for       innovation.

  3. Proven Project Leadership

    • Experience leading projects from hit identification to       preclinical candidate compound (PCC) selection.

    • Designed at least two drug molecules that have progressed to       Phase II clinical trials or beyond.

  4. Intellectual Property Expertise

    • Proficient in compound patent analysis and familiar with IP       protection strategies.

  5. Leadership and Team Management

    • Strong leadership and execution skills.

    • Proven ability to coordinate project teams and align internal       and external resources to drive efficient project progress.

  6. Personal Attributes

    • Self-motivated and career-driven.

    • Demonstrates strong commitment and passion for drug discovery       and development.


*Application email to:hr@cascadepharm.com
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